In a mixing bowl, combine ground chicken, garlic powder, onion powder, paprika, salt, black pepper, egg, and breadcrumbs. Mix until well combined.

Divide the mixture into 4 equal portions and shape them into patties.

Preheat the grill to medium-high heat.

Place the patties on the grill and cook for about 6-7 minutes on each side, or until the internal temperature reaches 165°F (75°C).

If using cheese, place a slice on each patty during the last minute of cooking to melt.

Toast the burger buns on the grill for 1-2 minutes.

Spread mayonnaise on the bottom bun, add the chicken patty, top with lettuce, tomato, and ketchup if desired. Place the top bun on and serve.